幹 is built from the 倝 (sunrise (in 幹·韓)), 人, and 干 components.
It reads カン like 干, as do 岸, 刊, 肝, and 汗 — learn 干 once and the family's reading comes with it.
A common word using 幹 is 新幹線 (しんかんせん), meaning “Shinkansen, "Bullet Train"”.
Kanji that look similar include 乾 and 潮.